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If you are taking Depakote during pregnancy for virtually any health care ailment, your baby is at risk for serious delivery defects that have an effect on the Mind and spinal twine (such as spina bifida or neural tube defects). These defects can commence in the 1st month, even prior to deciding to know you will be Expecting.
Table 3 lists procedure-emergent adverse reactions which were being described by ≥ 5% of Depakote-handled people and for which the incidence was larger than while in the placebo group, from the placebo-managed trial of adjunctive therapy for remedy of elaborate partial seizures.
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The following adverse reactions are already identified during put up approval use of Depakote. Mainly because these reactions are described voluntarily from the populace of unsure size, it is not often doable to reliably estimate their frequency or create a causal marriage to drug publicity.
If You can not swallow a sprinkle capsule whole, open it and sprinkle the medicine into a spoonful of pudding or applesauce. Swallow the combination without delay. Do not reserve it for afterwards use.
Valproate should not be used to treat Gals with epilepsy or bipolar problem that are Expecting or who prepare to be Expecting Except if other prescription drugs have unsuccessful to offer suitable symptom control or are if not unacceptable.
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Depakote get more info is contraindicated in individuals recognised to possess mitochondrial Diseases because of mutations in mitochondrial DNA polymerase γ (POLG; e.
Sufferers with urea cycle Diseases who are increasingly being addressed with sodium phenylbutyrate shouldn't acquire valproic acid. This conversation is often fatal.
Depakote tablets and capsules are employed to deal with seizures in people with epilepsy that are at least 10 years previous. The tablets are occasionally used together with other seizure drugs.
Usually do not start off or halt taking Depakote in the course of pregnancy with no your health care provider's advice. Divalproex sodium might damage an unborn little one, but using a seizure through pregnancy could damage both mother and baby. Do not use Depakote to stop migraine complications For anyone who is Expecting.